By Antin. The uterus is the pelvic organ that holds the pregnancy and that bleeds each menstrual period. The cervix is that part of the uterus fixed at the top of the vagina.

The uterus is divided into three parts :

· The wall of uterus that composed of smooth muscle

· Glandular epithelium

· Endometrial stroma

Glandular epithelium and endometrial stroma, together called Endometrium of uterus. The endometrium of uterus is hormonally sensitive and changes throughout the menstrual cycle and during pregnancy.

Types Of Uterine Cancers

Each parts of uterus can growth as uterine cancers. The smooth muscle cancers (wall of uterus) are called leiomyosarcomas. There is also a benign tumor of smooth muscle called a leiomyoma (also called myoma / fibroid) The endometrial stroma of uterus can growth to a variety of cancers classified as sarcomas. The cancers from glandular lining of uterus called adenocarcinomas.About 95 % of uterine cancers are adenocarcinomas that arise from the glandular epithelium cells.So if we talk about Uterine cancers, we refer to Adenocarcinomas.

Risk Factors for Uterine Adenocarcinoma

There are same risk factors for Cancer of uterus. The most important risk factor of uterine cancer is age. Almost all of uterine cancer happen in postmenopausal and perimenopausal women. There is also a well-recognized association with estrogen. prolonged unopposed estrogen stimulation to the endometrial glands and this will increase the risk for cancer of these glands. The increased of estrogen level can happen to postmenopausal and obese woman, woman who take Tamoxifen for breast cancer. Progesteron influence can decreased the risk of uterine cancer, so pregnancy and birth


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